While it’s no secret that issues with blood glucose level (BGL) control may lead to diabetes, research now indicates that gut bacteria may play a key role here.
Research published in Proceedings of the National Academicy of Sciences (PNAS) reveals that bacteria in the gut of mice communicates with cells in the gut that produce serotonin, which in turn has an impact on BGLs and metabolism.
“We found that the microbiome worsens our metabolism by signalling to cells in the gut that produce serotonin.
“They drive up serotonin levels, which we previously showed in humans to be increased in obese humans, and this rise in blood serotonin causes a significant metabolic problem,” explains Professor Damien Keating, Head of Molecular and Cellular Physiology at Flinders University and Deputy Director of the Flinders Health and Medical Research Institute.
While the research is a promising start to better understanding how bacteria communicate with serotonin to influence BGLs and metabolism, it’s not yet known which bacteria are involved in this.
“This is an exciting revelation that can one day have direct implications for human health disorders such as diabetes,” adds Professor Keating.
Professor Keating ends saying more research is needed.
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